Journal: Toxics

Article Title: PCB Exposure in Adult Male Mice Reduces Proliferating Cells in the Prostate but Minimally Alters Voiding

doi: 10.3390/toxics14030265

Figure Lengend Snippet: Adult PCB exposure does not alter caspase 3-positive cells in the prostate. Adult male mice were exposed to a daily dosage of the MARBLES PCB mixture for 2 months and tissues were collected for histology. Representative images of ( A ) anterior prostate, ( B ) ventral prostate, and ( C ) dorsolateral prostate stained with antibodies targeting cleaved caspase 3 (red) and E-cadherin (green, all epithelium) and counterstained with DAPI to label all nuclei (blue). Quantification of the percentage of total cells which are caspase3+ in the ( D ) anterior prostate, ( E ) ventral prostate, and ( F ) dorsolateral prostate. Arrows indicate positive cells. Results are mean ± SEM, n = 4–5 per treatment group. No significant differences p ≤ 0.05, as determined by a Kruskal–Wallis test.

Article Snippet: Cleaved Caspase (Casp3) , Rabbit , Cell Signaling , 9661 s RRID: AB_2341188 , 1:200 , .

Techniques: Staining